What is Acrocyanosis?
Acrocyanosis is an rare rarified status characterized by painless , symmetrical and haunting blue or royal discoloration of the skin and mucus membrane of the body . It mostly impress the peripheral extremity commonly involving the distal parts of feet , toes , ankles , hands and face .
Acrocyanosis prevails more in cooler geographic areas hence usually seen in population residing in the colder climatic regions . It is also observed in people who are take in outdoor job in such cold locations .
Acrocyanosis symptom are seen more in enervated females than Male , and young child ( newborns and preterm ) as they have down physical structure mass index ( BMI ) .
Etiology of Acrocyanosis
An accurate cause of Raynaud’s sign is still unknown . However , the most common theory proposes that the bluish pelt discoloration is due to constriction or narrowing of the little arterioles followed by vasodilation in venula web of peripheral extremities , to even up for the vasospasms in dermal arterial meshing do hypoxia and oxygen insufficiency .
There are two types of acrocyanosis :
Primary / Essential Acrocyanosis is a benignant disorderliness and not interrelate to any underlying disease or condition . It is also term as idiopathic acrocyanosis .
Secondary Acrocyanosis occur as an upshot of an underlying or an ongoing condition , like psychiatric disorders , cardiovascular experimental condition mostly stroke , myocardial infarction , coronary artery disease and endocarditis etc . and neurological or autoimmune disorders ( Rheumatoid arthritis , Lupus erythematous , Neoplasms ) . Metabolic disorders like antiphospholipid syndrome may stimulate cyanosis . multitude suffering with nervous and psychotic disorders are at in high spirits hazard of cyanosis . Depressive emotional behavior may aggravate the symptom . It may also be associated with some incidental medications like Amphotericin B , Clonidine , Tricyclic antidepressant drug , Benzocaines , Dopamine etc .
Acrocyanosis may show remission of sin and recurrence and usually presents with painful blue and reddish skin discoloration over extremity and may develop ulceration and gangrene .
The symptom can be aggravated by cold weather and trunk metabolic process .
Signs and Symptoms of Acrocyanosis
Signs and symptoms of acrocyanosis include :
Diagnosis of Acrocyanosis
Diagnosis is mainly based on the mark and symptoms . The other things considered while diagnosing the precondition includes :
The differential diagnoses which must be over - ruled for diagnosing Raynaud’s sign are :
Treatment of Acrocyanosis
Acrocyanosis is believe to have an splendid medical prognosis . The symptom of Acrocyanosis suppress with the warm clime and aggravates with cool temperatures . This experimental condition is not associated with any stark tortuousness of pre - existent symptoms or risk of death . There is no defined treatment for Acrocyanosis ; however , precautionary weather conditions and level-headed lifestyle would help prevent acrocyanosis . In case of secondary Raynaud’s sign , the underlying disorder would require the corresponding discussion to cure the symptoms .
medication like vasodilator alpha blocker mainly Carvedilol , Tamsulosin etc . and calcium distribution channel blocker like Amlodipine , Nifedipine etc . may play a major use in get rid of vasoconstriction in peripheral artery ameliorate the O adequacy and tissuehypoxia .
Also interpret :
