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Acute Phosphate Nephropathy

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Kidneys- A lively organ of our dead body whose function is to empty the permissive waste of physical structure . In vitrine thekidneystarts malfunctioning , the waste present in our torso does not get throw out ensue in a variety of complicatedness . One such stipulation is Acute Phosphate Nephropathy , in which there is damage to kidneys as a result of organization of phosphate crystals in renal tubule potentially damaging nephrons leading to potentialAcute Renal Failure.1In this clause , we will register about the various factor leading to Acute Phosphate Nephropathy , the various symptoms , risk of exposure factor of Acute Phosphate Nephropathy .

How Is Acute Phosphate Nephropathy Defined?

According to the FDA , Acute Phosphate Nephropathy is a type of a kidney harm which is caused as a upshot of formation of Ca orthophosphate lechatelierite in renal tubules , which has the potentiality to make lasting hurt to the nephritic function . Acute Phosphate Nephropathy is pretty rarified , but a potentially serious result which has been associated with the use of Oral Sodium Phosphate ( OSPs ) , which is broadly used for bowel cleaning before a procedure .

What Are The Causes of Acute Phosphate Nephropathy?

As mentioned , Acute Phosphate Nephropathy is generally associate with consumption of Oral Sodium Phosphate like C.B. Fleet ’s Phospho soda ash commonly used for gut cleansing before a colonoscopy procedure.1The risk of infection element for developing Acute Phosphate Nephropathy is shrewdly increased with age , dehydration , or when an soul has high blood pressure .

What Are The Risk Factors for Acute Phosphate Nephropathy?

individual with greatest risk for spring up Acute Phosphate Nephropathy are hoi polloi above the age of 50 , already have a kidney function problem and have undergone dialysis . Also , multitude with electrolyte dissymmetry or other kidney disease are at jeopardy for developing Acute Phosphate Nephropathy .

What Are The Signs and Symptoms of Acute Phosphate Nephropathy?

It is extremely of import that masses who take Oral Sodium Phosphates have knowledge of signs and symptom of Acute Phosphate Nephropathy . Some of the signs and symptom are :

Diagnosis for Acute Phosphate Nephropathy

Acute Phosphate Nephropathy usually present in the form of Acute Renal Failure with some amount of albuminuria in people who have recently consumed OSPs . When a kidney biopsy is conducted , it may give away incisive renal tubular damage , deposition of calcium phosphate crystals , etc . These pathologic identifier are reproducible with a condition called Nephrocalcinosis .

What Factors Should A Healthcare Professional Consider Before Choosing A Bowel Cleanser For Patients?

Any Dr. should take the surveil safeguard when choosing a bowel cleaner for patient :

How to Reduce Risk of Developing Acute Phosphate Nephropathy?

patient can lour their chance of develop   Acute Phosphate Nephropathy by :

Treatment for Acute Phosphate Nephropathy

Because the good treatment is still under research for Acute Phosphate Nephropathy , there is no clear cut treatment , but avoiding potential hazard factors for Acute Phosphate Nephropathy can help a long way in preventing this potentially serious disease .

References-

1 . Phosphate rush crystal acute kidney injury – an under - recognized cause of acute kidney wound potentially leading to chronic kidney disease : case report and critique of the literature .

Lochy S1 , Jacobs R , Honoré Prime Minister , De Waele E , Joannes - Boyau O , De Regt J , Van Gorp V , Spapen HD .

Int J Nephrol Renovasc Dis . 2013 Mar 16;6:61 - 4 . doi : 10.2147 / IJNRD.S41428 . Print 2013 .

2 . Is bowel preparation before colonoscopy a wild business for the kidney ?

Lien YH .

Nat Clin Pract Nephrol . 2008 Nov;4(11):606 - 14 .

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