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Alagille Syndrome

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Alagille Syndrome- This is an inherit medical condition usually found in children . Disease make progressive going of bile ducts within the liver leading to excessive accrual of gall in theliver . The liver abnormalities result in legion medical complications , includingcirrhosisof the liver . In this article , we will discuss in point about the various causes , symptoms , and discourse for Alagille Syndrome .

How Is Alagille Syndrome Defined?

Causes Of Alagille Syndrome

Genetic Disorder-

Narrowing of Bile Duct-

Symptoms Of Alagille Syndrome

Non-Specific Symptoms Of Alagille Syndrome:

Specific Symptoms Of Alagille Syndrome:

Diagnosis of Alagille Syndrome

Diagnostic Criteria-

Treatment For Alagille Syndrome

Medications-

MCT Oil-

Vitamin Supplement-

Surgery-

References :

1 . Alagille syndrome : an overview .

Vajro P1 , Ferrante L , Paolella G.

Clin Res Hepatol Gastroenterol . 2012 Jun;36(3):275 - 7 .

2 . Renal anomalies in Alagille syndrome : a disease - determine feature article .

Kamath BM1 , Podkameni G , Hutchinson AL , Leonard LD , Gerfen J , Krantz ID , Piccoli DA , Spinner NB , Loomes KM , Meyers K.

Am J Med Genet A. 2012 Jan;158A(1):85 - 9 . doi : 10.1002 / ajmg.a.34369 . Epub 2011 Nov 21 .

3 . Alagille syndrome and other hereditary cause of cholestasis .

Hartley JL1 , Gissen P , Kelly DA .

Clin Liver Dis . 2013 May;17(2):279 - 300 .

4 . Perthes - like disease in Alagille syndrome .

Massobrio M1 , Antonietti G , Necci F , Esposito C.

J Pediatr Orthop B. 2011 Sep;20(5):299 - 302 .

5 . direction of cholestatic pruritus in pediatric patient with alagille syndrome : the King ’s College Hospital experience .

Kronsten V1 , Fitzpatrick E , Baker A.

J Pediatr Gastroenterol Nutr . 2013 Aug;57(2):149 - 54 . doi : 10.1097 / MPG.0b013e318297e384 .