What is Alexander Disease?
Alexander Disease is a rare pathologic term of the skittish scheme which is in reality a collection of a grouping of disorder know as leukodystrophy in which there is monumental demolition of medulla . Myelin is a fatso covering that acts as an insulator for nerve fibers and facilitates transmission of brass impulse from the brain to various parts of the body . When there is demolition of myelin this transmittal of heart impulses becomes impaired lead to various tortuousness like a complete impaired nervous system which means that the affected patient is virtually disabled and not in a stipulation to perform any activities voluntarily .
What are the Causes of Alexander Disease?
In most of the case , Alexander Disease is not inherit which means that the kid suffering from Alexander Disease has not got it from his or her parents even though the parent may have a bad gene in them . The root cause of Alexander Disease is noted to be a flaw in gene call Glial Fibrillary Acidic Protein or GFAP . This is a protein which is involved in structural development of cells and a mutation in this factor is creditworthy for the developing of Alexander Disease .
What are the Symptoms of Alexander Disease?
The symptom of Alexander Disease are variable and depend on when the condition develops think of whether the consideration develops in infantile , puerile , or adult onset . The severity of the symptom may depart depend on the extent of the disease and how much the disease has scatter .
Symptoms of infantile form of Alexander Disease are :
The symptoms of adolescent form of Alexander Disease are :
The symptoms of adult - onrush Alexander Disease are
How is Alexander Disease Diagnosed?
If Alexander Disease is suspected based on the signs and symptom shown by the patient , a simple-minded genetic examination is enough to sustain Alexander Disease as the bad gene stimulate this shape is well bang and can be easily identify on genetic testing and can reassert the diagnosis of Alexander Disease .
How is Alexander Disease Treated?
regrettably , there is no cure for Alexander Disease as of yet . The treatment for Alexander Disease is basically symptomatic and supportive . sealed conditions like capture and hydrocephaly can be treated . ictus can be controlled with antiepileptic medicinal drug while hydrocephaly can be handle with operating theater to enfeeble piss from the brain and thus relieve the pressure put on the brain by the body of water roll up inside it . On an observational basis , bone marrow transplantation has been adjudicate as a treatment for Alexander Disease but it has not been obtain to be much successful .
What is the Life Expectancy from Alexander Disease?
The life history anticipation of a patient with Alexander Disease depends on the attack of the status . Children with infantile Alexander Disease may not inhabit beyond one to two years of life and even if they do , they can go up to upper limit of 10 years . tiddler with juvenile form of Alexander Disease be given to live up to midway age after the diagnosis of Alexander Disease .
