Vitamin B12 is a penis of the water - soluble vitamin of the B complex grouping . It is also known as vitamin B12 . It is mainly derive from dietary aspiration of food of brute lineage such as center , eggs , fish and domestic fowl , other artificial products fortify with the vitamin . The micronutrient is required in the body for production of red blood cadre , regulating of homocysteine metabolism , manufacture of DNA ( genetic fabric ) and right mental performance .
Regulation of Vitamin B12 Levels in the Body
Upon dietetic consumption of foods copious in the vitamin , and being water soluble , it easily moves across the gut lumen into circulation by combat-ready transport and dispersal aided by a protein known as intrinsical broker . It is then transported in the physical structure by the help of transcobalamin . Hence , want can occur with decent intake in grammatical case where there is lack of transporting corpuscle ( pernicious anemia ) or when the function of the gut is compromise such as after gastric surgery for weight loss and in diseases such asCrohn ’s diseaseandceliac disease . However , the tumid cause stay inadequate dietary intake as construe with perfect vegetarian diet . Up to 3 mg can be suck from the dieting everyday , but only 2 to 3 mcg is ask by the dead body to undertake various functions and replenish the fertile vitamin B12 reserve of up to 30 milligram that is base in an adult human body , thus deficiency of vitamin B12 requires a long metre to occur .
exuberant levels of vitamin B12 may also be noted in circulation and this suggests the possibility of disorder such as chronic liver disease , chronic kidney disease or myeloproliferative disorders . These patient must be monitored for Ca want .
Can Vitamin B12 Help in Lowering Blood Pressure?
Association of Vitamin B12 Levels and Blood Pressure
Vitamin B12 has an indirect family relationship with tissue paper oxygenation as it is required in the fabrication of mobile phone used in the delivery of O and nutrients to peripheral tissues ( red blood cellphone ) . A reduction in the level of vitamin B12 in circulation leads to slenderize blood-red blood cell production and hence short tissue paper perfusion . This get an increase in blood pressure as the trunk tries to perfuse the tissue by increasing the amount of blood that reaches peripheral tissues .
In addition to this , reduction of vitamin B12 in the body lead to increase in the layer of homocysteine . This amino group dot is like a shot connect with heart nonstarter and stroke as well as the intermediate land of grand blood press as demonstrated by the American Heart Association ( AHA ) . Homocysteine increases the growing of coronary artery disease that causes arterial wall thickening and reduction in compliance necessitates the step-up in blood pressing to overcome this resistance contribute to hypertension .
Benefits of Vitamin B12 Supplements in the Control of Blood Pressure
give the direct relationship of low vitamin B12 levels and hypertension , vitamin B12 supplementation is being carry out on a contraceptive basis in various clinics , more so the weightiness passing clinics as these patients are at a higher risk of infection of developing vitamin deficiency compared to the ecumenical population .
Deficiency is indicated by onset of signs and symptoms such as megaloblastic anaemia altered sensations and abnormal behavior . subjoining can be enteral , but parenteral itinerary are preferred in patient role whose guts may not be fully functional as absorption is not optimal .
Conclusion
Therefore , vitamin B12 is a H2O - soluble vitamin with body military reserve enough to last more than 6 calendar month without any further breathing in . The vitamin is critical for body part such as red line cell production and homocysteine regulating , which provide a direct regularization of atherosclerosis and bloodline pressure control .
To forestall the occurrent of hypertension secondary to vitamin want , parenteral supplements are carried out in patients at risk such as those under weightiness loss clinic follow - ups after gastrectomy .
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