The food which we eat is made of carbohydrates , fats and protein . The digestion of food for thought involves breaking down of the complex substances into unsubdivided centre which can be immerse easily by our body . Digestion begins in the mouthpiece where the nutrient is chewed and mixed with the spit . It further move into the GI tract which consists of the stomach , pancreas and small intestine . In the stomach , the food is mix with Zen and proteins are broken down . While in the modest intestine , the food for thought gets completely digest with service of enzyme released from pancreas and bile produced by thegall vesica . The digested food is absorb by the cellular telephone of belittled intestine and is circulated in the consistence to supply nutrient .
What is Exocrine Pancreatic Insufficiency?
Pancreas is a gland with an endocrine and an exocrine function . Endocrine mean it produce and let go of internal secretion into the blood flow . It free endocrine like insulin and glucagon to regulate the blood glucose levels . While exocrine entail pancreas cells produce enzymes which are released into the small intestine for digestion of the complex solid food heart . It put out enzyme such as :
These simple product of digestion are absorbed by the little intestine and provide to the body .
Exocrine Pancreatic Insufficiency ( EPI ) is a medical condition where the pancreas is not able to release sufficient amount of enzymes into the minor intestine . Due to certain fundamental medical intellect , the exocrine gland function of pancreas is halter . This impairs the digestion process of food for thought , principally the equipment failure of the lipids or fatty tissue . Since the solid food is not properly condense , it does not get absorbed and gives rise to a number of symptom . Both malabsorption and malnutrition affects a mortal ’s overall health and well - being . The good thing is that exocrine pancreatic deficiency is treatable .
Symptoms of Exocrine Pancreatic Insufficiency
Exocrine pancreatic insufficiency cause following symptom :
Causes of Exocrine Pancreatic Insufficiency
The following are some of the causes which lead to deficient pancreatic enzymes thus pay rise to exocrine pancreatic deficiency .
Chronic Pancreatitis : It is long term inflammation of the pancreas because of inordinate potomania or gallstones . In some cases it can be autoimmune . The cells of pancreas get damaged which results in insufficient secretion of pancreatic enzyme for digestion .
Cystic Fibrosis : It is a genetic disease which results in secretion of thick and sticky mucus which pretend the lungs and the digestive system of rules . The mucous secretion build up to block the opening move ( duct ) of pancreas , due to which the enzymes do not reach the small intestine and this affect digestion .
Shwachman - Diamond Syndrome : The pancreas does not have enough cells to raise enzymes . This results in insufficient enymes for process of digestion .
Pancreatic Cancer : This can lead to duct gland pancreatic insufficiency .
Crohn’sandCeliac Diseasealso chair to Exocrine pancreatic insufficiency in some masses .
Surgical remotion of pancreas .
Diagnosis of Exocrine Pancreatic Insufficiency
Doctor will execute physical interrogation and enquire relevant questions . He will also require for further run such as :
It is necessary to diagnose Exocrine pancreatic insufficiency since some of its symptom are same as those of other gastrointestinal nerve tract problems such asirritable bowel syndrome , ulcerative colitisand lowly enteric bacterial gigantism .
Treatment of Exocrine Pancreatic Insufficiency
After diagnosing , the treatment for Exocrine pancreatic insufficiency should be started instantly . It involve taking Pancreatic Enzyme Replacement Therapy ( PERT ) . The medicine for Exocrine pancreatic inadequacy includes the enzymes from porcine pancreas to be taken in tablet form during all meals and snacks . The six US - FDA approved enzymes which are available by prescription include : Creon , Pancreaze , Pertzye , Ultresa , Viokace and Zenpep . These enzymes take up the function of pancreatic enzymes and assist in digestion of food for thought . This treatment for Exocrine pancreatic insufficiency is efficacious and allows person to digest food for thought , absorb nutrient and have a good quality of lifetime .
In addition to the PERT treatment , the person suffering from exocrine pancreatic inadequacy should take attention of the following :
Conclusion
duct gland pancreatic deficiency needs to be treat by rights or else it will make growth problems in infant and a pathetic prospect due to unfitness to fight infections . The symptoms of duct gland pancreatic insufficiency can be managed with the right and other treatment such as the pancreatic enzyme replacement therapy . One want to confer a nutritionist to keep up a right nutrition to remain well - nourished and to prevent deprivation of weight .
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