What is a Factor V Leiden?
gene V Leiden is an inherited disease . Factor V Leiden is a type of pedigree clotting disorder , which is a mutation of Factor V Protein . Sudden alternation in the protein component V increases the possibility of evolve abnormal roue clots especially in the veins . Majority of the great unwashed suffering from Factor V Leiden do not face abnormal clotting problem , but people who develop clot also face various wellness issues including some life jeopardize ones .
man and cleaning lady both are equally prone to Factor V Leiden . People suffering from Factor V Leiden are often prescribed anticoagulantmedicationsto lowly the risk of exploitation of extra rake clots .
roue clothelps in stopping redundant current of blood when there is any price in the vena or artery . Blood clot forms as a termination of response that withdraw office between stock blood platelet and protein present in blood cells .
How Rare is Factor V Leiden?
Possibility of having Factor V Leiden is very vulgar among mass , but only 10 % of them go through abnormal blood clotting . Hence , as compared to otherhereditarydisorders , this is rarely notice in individuals .
What is Heterozygous Factor V Leiden Mutation?
As discourse above Factor V Leiden is a disorder do unnatural lineage clotting and it is a hereditary disease . People who receive one copy of bad gene from their parent are experience as heterozygous . On the contrary , the citizenry inheriting two copies of bad genes are known as homozygous . Research has evidence the fact that hoi polloi with heterozygous Factor V Leiden mutation 3 to 8 times more prostrate to develop venous thromboembolism and people with homozygous genetic mutation have 50 to 80 time more peril of thrombosis .
What is Factor V Deficiency?
Factor V is an essential component of blood , insufficiency of this can make bleeding disorderliness . want of Factor V is also know as Owren disease , because Dr. Owren was the one who first identified this issue in the class 1943 . divisor V deficiency leads to slow down the process of blood line coagulation after combat injury , which ultimately head to superfluous blood loss from the body and can lead to death . There are high possibilities that Factor V Deficiency and Factor Vlll Deficiency cause at the same time creating serious blood clotting outlet . However , the medical scientific discipline look at them as two different upset .
Causes of Factor V Leiden
Factor V is a coagulate protein and the anti - clotting protein present in the body break Factor V , which direct to establishment of clots when clotting is not even demand . Factor V Leiden makes it very difficult for anti - protein to breakdown Factor V. This manner Factor V remains for long in stemma and also the possibility of clot formation increase well .
citizenry with Factor V Leiden , either inherit one copy of bad gene from one parent or in some uncommon cases inherit two copy ( one from each parent ) of defective genes . People with one copy of faulty gene become somewhat prostrate to grow blood clot , but multitude with two copies have high risk of developing abnormal bloodline clots .
Symptoms of Factor V Leiden
developing of blood clots is the first and the most pregnant symptom of Factor V Leiden . Some clot are not harmful as they appear and then disappear on their own . On the contrary , some coagulum are very severe and can be serious . Symptoms of line clots depends on where it is developed and whether it travels or not .
Tests to Diagnose Factor V Leiden
Doctors principally suspect Factor V Leiden if patient has either suffered multiple instances of abortion or have a strong folk history of thrombotic disease . medico dictate blood trial for diagnosing of this mortal disease . Two types of blood tests are prescribed .
For the great unwashed who are on blood - thinning medication are only prescribed to go for genetic test as blood - thinning medication obstructs the accurate result of APC i.e. , activated protein ampere-second underground test . These tests are not commend to novel endure nestling , rather ; it is only prescribed to adult .
Treatment for Factor V Leiden
People suffering from this blood clotting disease of Factor V Leiden are often prescribed to have blood thinning medication such as Lipo-Hepin , warfarin and so on . If genetic mental testing turn up that you have Factor V Leiden that does not lead to geological formation of blood clots then MD may not advice parentage thinning medicament on regular basis , but will advice a finical dose to prevent DVT .
Diet for Factor V Leiden
People suffering from Factor V Leiden should include more of the food that helps in blood thinning . Food gamy in Salicylates should be included in dieting as it blocks the receptor of vitamin K and add in blood thinning .
Home Remedies for Factor V Leiden
breathing in of goodish balanced dieting and exercising on a regular basis help in maintaining proper rakehell flow in the organic structure and forbid blood clotting and is the respectable home redress for Factor V Leiden .
Person suffering from this disease should avoid to be in a particular office ( either sitting or standing ) for long point of time as it stymie line of descent circulation . They should also forfend solid food that lead in blood clotting .
Recovery Period/Healing Time for Factor V Leiden
There is no pre - defined recovery period or healing time for Factor V Leiden because this blood disorder pass off because of front of defective gene in the body . The only matter one can do is to take few prophylactic meter for profligate clotting and should be on right medication .
Prevention of Factor V Leiden
As Factor V Leiden is a genetically transferred disorderliness , hence there is no effective prevention measuring stick for the same . acquire a healthy life-style and taking rest diet can control the job to some extent .
Risk Factors for Factor V Leiden
Factor V Leiden a hereditary upset , so people who have a family history of Factor V Leiden are at high danger of inherit the disorder . White people of European descent are more prone to inherit this problem .
Can you Give Blood if You Have Factor V Leiden?
Yes , the masses suffering from Factor V Leiden or from any other type of thrombophilia can easily donate their rip plasm or platelets . However , if the someone feign with Factor V Leiden is on Coumadin ( anticoagulant medication ) then in this situation doctors do not advice to donate blood , as it can create complications for blood receiver .
Complications of Factor V Leiden
There are various tortuousness associated with Factor V Leiden . Some of the vulgar complication are :
Prognosis/Outlook for Factor V Leiden
The prognosis or outlook for Factor V Leiden is salutary . Development of bloodline clot is the first indication that person is suffering from Factor V Leiden and when this coagulum develop near the aerofoil of skin , it create lovingness , swelling and inflammation in that area .
Lifestyle Changes for Factor V Leiden
Some simple lifestyle change can in reality be very fruitful in preventing blood clots due to Factor V Leiden . They are as follows :
