Fraser Syndrome – This is a relatively rare medical experimental condition in which there is visible webbing of the fingers and toes , renal dysfunction , genital malformationsetc . Fraser syndrome is know by other various name like Cryptophthalmos - Syndactyly Syndrome , Cryptophthalmos Syndrome , and Cyclopism among others .
What Is Fraser Syndrome?
Fraser Syndrome as posit is a rare genetical condition in which there is seeable webbing of finger and toes . There is also nephritic disfunction , venereal malformation , and in some instance total fusion of eyelids , a precondition called as cryptophthalmos , which may result in blindness . In infant involve with Fraser syndrome , nephritic abnormality may need inadequate developing or hypoplasia and even absence ofkidneyswhether a solitary kidney or both the kidney . In males with Fraser Syndrome , the testis may not to descend enough into the scrotum , there may be presence ofhypospadias , and the penis may be extremely small . In females with Fraser Syndrome , there may be presence of clitoromegaly or abnormally shapeduterus . to boot , there may also be comportment of ear dysfunction resulting in hearing problems . Fraser Syndrome is an autosomal recessivegenetic disorderliness , which think that both parents require to have the affected gene cause Fraser Syndrome .
Causes of Fraser Syndrome
As stated , Fraser syndrome is an autosomal recessionary upset . The altered gene has been stated to be present in recollective subdivision of chromosome 4 ( 4q21 ) . Chromosomes present in core of human cells have genetic information for every person . By Autosomal Recessive , one think of that the abnormalcy is inherited by the chromosomes of both parents .
Symptoms of Fraser Syndrome
If an individual is affected with Fraser Syndrome , then that individual will have visible physical irregularity , which can include complete fusion of the eyelids causing a condition call as cryptophthalmos , missing kidney , net fingerbreadth or toes . Some of the other defects associated with Fraser Syndrome are hair growth stretch out from forehead to eyebrows , malformation of eyelid ducts , wide space nipples , along with genial deadening . There may also be inadequate development of the genitals
Diagnosis of Fraser Syndrome
Diagnosis is commonly made on a detailed physical examination and account pickings , especially if there is a home history of Fraser Syndrome . substantiation of the diagnosing is pretty seeable with the deformities mentioned above and can also be confirm by imaging studies .
Treatment for Fraser Syndrome
Treatment of Fraser syndrome mainly involve operative process to correct the strong-arm deformity involved with this Fraser Syndrome . Apart from operating room , other treatment are generally supportive . Genetic guidance is ordinarily beneficial for parents of children strike with this Fraser Syndrome .
