What is Hemophilia?
Hemophilia is an inherit pathological condition in which there is an abnormality in the pedigree ’s power to clabber adequately . Hemophilia is commonly get as a result of some abnormality in the protein which cause the parentage to clot . These proteins are called as clotting factors . Since the blood is not able to clot easily in Hemophilia even a small cut or abruisewill cause hemorrhage that will be toilsome to stop . The clot factor or protein work in tandem with the platelet to allow the blood to clot . It is estimate that about one in every 10,000 masses born is born with Hemophilia .
People with Hemophilia not only phlebotomise easily but may also stand from interior bleeding as well and tend to have painful swollen joints due to bleeding within the articulation . Hemophilia is a rare experimental condition but it tends to have potentially serious life threaten complications . There are basically three types of Hemophilia namely A , boron , and C of which Hemophilia A is the most common character and is because of deficiency of gene VIII in the blood line .
Hemophilia B is cause by deficiency in gene IX and Hemophilia C is due to deficiency in cistron XI is the much milder form of Hemophilia . People with Hemophilia C do not experience any spontaneous bleeding which is the case with the other two case of Hemophilia . Hemophilia does not have a cure as it is an inherit status and the discussion is aimed at minimize the symptom and keep any complication caused due to Hemophilia .
What Causes Hemophilia?
The clotting process starts as soon as there is an injury or wound in the eubstance . This takes place with the platelets coming together at the combat injury site and forming a coagulum . Once this process is over then the curdling factors starts acting and have a permanent clot till the combat injury heals . Hemophilia is caused when these clotting agent are not enough in the organic structure result in the wound not being properly clotted and the bleeding continues .
As stated , Hemophilia is a genetic term and an individual is carry with it . This status is because of a fault in the gene which take a crap factors VIII , IX , and XI which is essential for clotting factor . It is an X - linked autosomal recessionary trait . Since X - linked chromosomes are find in female hence female person are called as the immune carrier of the defective gene . male person get this defective gene from their mother signify that the male which has inherited the factor from the mother will have Hemophilia .
Any female person with the factor fault do Hemophilia will have a 50 % or more chances of passing this defective gene to her children . female who have the faulty gene are termed as carriers of Hemophilia intend that the female person herself will not have the disease condition but may very well pass on to her offspring after on . In cause where males have the defective factor in the X chromosome then they pass the factor on to their girl make them a toter of the defective factor get Hemophilia .
On the other hand , male person who have tenner chromosome and have a faulty cistron have every hazard of passing these defective gene to their daughters who will then become postman of this defective factor cause Hemophilia .
What are the Symptoms of Hemophilia?
How bad the symptom of Hemophilia will be depends on the badness of the coagulation component want . soul with mild case of Hemophilia may only hemorrhage after a injury or an accident while people with terrible deficiency of coagulation gene may begin bleeding spontaneously . In cases of spontaneous hemorrhage the mortal may experience the following symptom .
How is Hemophilia Diagnosed?
stemma test is the good way to name Hemophilia . A modest amount of rake is taken from the patient and sent for analysis to determine if there is a clotting factor inadequacy . This test will confirm the diagnosing of Hemophilia and the blood test will also quantitate the clotting factor deficiency and avail the Dr. set the severity and formulate a intervention programme for Hemophilia .
How is Hemophilia Treated?
Hemophilia A which is the mild bod of Hemophilia can be treated with shot of hormones which increase the curdling efficiency of the blood line and helps in earlyblood clotting . This internal secretion is call desmopressin . In case of Hemophilia B , the physician may recommend extract of clabber factors from potential presenter . For Hemophilia C which is the most stern pattern of Hemophilia , plasma infusion is recommend to try and keep profuse haemorrhage , although this medicinal drug is very knockout to get hold at this sentence in the United States . For cases where the joints get tight and are painful due to Hemophilia , physical therapyis commend by the physician to cut down the damage because of Hemophilia .
