About Pernicious Anemia
Anemia is a common pathologic term characterized by abnormally downcast reckoning of ruby-red blood cells or hemoglobin . There are dissimilar types of genus Anemia , of which , one that is caused as a result of vitamin B12 inadequacy is term as Pernicious Anemia . This type of anemia is caused as a result of the body ’s unfitness to absorb vitamin B12 required for yield of red blood cells .
Pernicious Anemia is quite uncommon in nature with less than 1 % of spherical population being regard by this condition . This commonly occurs in individual above the age of 60 . The term “ pernicious ” was give to this circumstance since there was no cure for this disease previously . However , this condition is easy do by now with vitamin B12 supplementation or injections .
If Pernicious Anemia is left untreated , it can lead to many potentially serious complications . amount to suit , gastritis especially atrophic gastritis is consider to be the elemental cause behind the growing of Pernicious Anemia .
How Does Gastritis Cause Pernicious Anemia?
Gastritis , especially Atrophic Gastritis develops as a consequence of gradual inflammation of the facing of the tummy . The primary crusade for Atrophic Gastritis is contagion make by H. Pylori bacterium .
The intrinsical component is a special type of protein which is present in the intestines . This special protein is super useful in absorbing vitamin B12 . When an individual has Atrophic Gastritis , the consistence is not capable to make adequate amounts of Intrinsic Factor protein . The lack of enough amounts of Intrinsic Factor protein results in sham the dead body ’s ability to completely absorb vitamin B12 . This over time results in vitamin B12 insufficiency and ultimately Pernicious Anemia . In ratiocination , gastritis is the primary cause of Pernicious Anemia . As a result of gastritis , the body loses its ability to engross vitamin B12 do vitamin B12 inadequacy which ultimately results in development of Pernicious Anemia .
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