Lyme disease is stimulate by the transfer of bacteria in the human by the vector . Ticks are the vectors and the reservoir for these bacteria is computer mouse and cervid . The bacterium come in in the tick when they prey on the reservoir . When these transmitter ticks provender on the mankind , the bacterium procreate and go in in to the homo . Various immunological reactions occur in the body against the bacterium which results in pyrexia and inflammation and also clinical neurology and cardiac effects . The bacteria may also fudge the immune system type B changing the surface antigen so that immune cells are ineffective to recognise the bacteria .
How Is The Body Affected By Lyme Disease?
The transmission is because of the bacteria Borrelia . This bacteria has got amazing ability to survive in both the vector body as well as the legion body . It is interesting to that both the vector and host bodies are significantly different from each other . Even these environmental diversity , the bacterium survives . Different challenge for the natural selection of bacteria in both transmitter and host threatens the macrocosm of bacterium . For example , ticking suck up blood almost two meter in a year . Thus , to survive in the vector with minimum alimentation is a challenge . Further , human body turn back a variety of highly advanced immune system of rules cells which would kill the bacteria . Thus , the challenge is to survive in the human body by elude the resistant organization .
When the spirochete are inject in the human by tick , an inflammatory rash , known as erythema migrans develop . This bacteria make to the various organs of the body such asjoints , nervous system and center . The immune system of the soundbox tries to kill the bacteria and if the immune system fails , the contagion ensues . It is interesting to remark that this bacterium does not have any toxin or pyrogen such as lipopolysaccharide rather it hold a sort of lipoproteins . These lipoprotein are responsible for initiating the instigative mental process in the organic structure . Further , B cells have their effect on the resolution of the symptom ofarthritis .
The complications at various sites such as joints , nervous electric cell andheartis due to the body ’s response to free various chemical substance in response to the intrusion of bacterium at these place . This causes inflammation and swelling of joints and also make tendonitis and carditis . Macrophages also play a major office in phagocytosis of bacteria . In spite of these immune responses , the bacteria win in evading the resistant system . The accurate case of this is unknown however the proposed mechanism for evading immune arrangement is through continuous alteration in the surface antigen .
Symptoms of Lyme Disease
Circular Red Rash Around The Tick Bite : The rash may seem even after 2 to 3 hebdomad from the ticking bite day .
FEVER : As the immune system starts fight against the contagion there is a rise in the body temperature .
Muscle And Joint Pain : Joint Pain is an important symptom in Lyme disease as the contagion may touch on the joint and related muscularity .
Neurology : In character of severe transmission and when the infection is not treated in the early stage , nervous organisation also gets affected .
Cardiac issue : Cardiac abnormalities also occur in character of dangerous infections .
fatigue , fatigue and headache are other symptom of the Lyme disease .
The symptom in the Lyme disease is in the main due to the immunological response to bacteria . The symptoms may let in the febricity and headache . Further , organ specific symptoms are inflammation and swollen spliff , tendonitis , neurological disorders and cardiac abnormalities . The chemical mechanism by which bacteria evades the resistant organisation is not known but it is pop the question that it does by change airfoil antigen . However , the disease can be effectively treated with recommended antibiotic therapy .
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