Lead is a lumbering metallic element that dally no function in human physiology , so the ideal plasma level should be zero . At present it is practically impossible to find any individual in whom blood line lead levels are not detected .
The World Health Organization ( WHO ) defines intoxication as the jumper cable poisoning values of more than 15 μg / dl . For the Center of Disease Control ( CDC ) the level of intoxication is with child or adequate than 10 μg / dl .
star intoxication produce metabolic disorder straight off related to its concentration . The alterations can lead to death and in variegate degrees of deterioration of rational mental ability , changes in behavior , stoppage of hematopoiesis , renal toxicity and peripheral neuropathy . These alterations are more harmful in children .
How Long does it take to Die from Lead Poisoning?
Exposure to this metal produces metabolic disorders that are strictly related to to its assiduity in the body . The level of toxic condition is neat or adequate than 10 μg / dl , affecting all the dead body . If the booster cable intoxication is spartan and not treated on time , it will make end . This depend on a serial of below bring up gene .
booster cable toxic condition constitutes a serious public wellness problem , since it affects the most vulnerable population : baby , workers and people of low socioeconomic status .
The absorption of hint come in the main in two ways :
The gastrointestinal path depends on age , diet , nutritionary want . In the adult , it is estimated that 5 % to 10 % is absorbed at the gastrointestinal floor . On the other hand , the child is 40 % to 50 % because of the mental attitude of the nipper to take everything to their mouth .
With respect to nutritional deficiencies , down in the mouth in iron and atomic number 20 and rich in lipids - diets favor lead absorption .
The airway is the master one in the work environment ; this is soak up by approximately 90 % . This route is of great importance in cities with a in high spirits concentration of automobiles and in proximity to metal - casting mill .
The distribution occurs in two compartments : the first is the skeletal system , which contain 80 to 95 % of the consistence trail burden , with the average life in the bone being 20 to 30 years . In kid it is deposited in the metaphysis of tenacious bones , forming radiopaque deposits .
The second compartment is in the soft tissue paper such as the kidney , brain and liver , being in these the half - life of 20 to 30 Day . In the roue it is find in stemma blood-red cell , this being the main compartment responsible for lead perniciousness .
A noteworthy fact is that lead crosses the placenta , contain fetal blood 80 to 100 % of the maternal lead .
The form of Pb toxic condition presentation of the symptom can be sharp or inveterate . Acute lead intoxication is an infrequent presentation and may be due to ingestion of contaminated solid food or to massive inhalation of lead vaporization .
In minor , the most frequent form of lead poisoning presentation is acute encephalopathy , which can look without prodrome or be forgo by abdominal cramping or conduct adjustment . It is demonstrate by lasting puking , ataxia , intractable capture , modify consciousness and comatoseness . deathrate is approximately 25 % and children who hold out are leave alone with neurological sequela such as epilepsy , mental retardation , dystonia , optic withering and deafness . At the renal level , an acute failure occurs due to tubular damage and occasionally it presents as a “ Fanconi syndrome ” . At the GI level , it can present with abdominal pain and intense vomiting , which can conduce to “ shock ” .
continuing Lead Poisoning : It is the most frequent form of presentation in both nestling and adult . The symptoms are nonspecific , in the main affecting the nervous , GI , renal , hematopoietic and neuromuscular systems .
In the earthly concern , lead poisoning is considered a serious public health job . It has capital importance in the paediatric age since the harmful effects occur in the neurophysical development stage . This force the baby doctor to keep in mind the existence of this insobriety , so it is all-important a correct environmental history in children with clinical element compatible with tether poisoning . behavioural disorders , intellectual deficit , hyperactivity , school delay , renal pathology and anaemia are the main alterations evidenced . The treatment must be directed by a multidisciplinary squad .
