Liver is the secondly expectant organ that is posit in the proper upper quadrant of the abdomen , below the diaphragm and overlying gallbladder , piece of pancreas and stomach . Liver is a critical organ that aid support nearly every other organ . Liver has over 500 functions in the body and the major map include digestion by the production of bile ( helps in fat digestion ) , metamorphosis , detoxification , quondam RBCs destruction , protein synthesis , regulation of hormones , to name a few . The failure of liver to behave out its functions due to demolition / damage of its cells bear upon nearly all the organs .
Causes and Symptoms of Liver Failure
Liver nonstarter is a life - threatening medical emergency and requires prompt intervention . Although , liver-colored bankruptcy is a dim process and build up gradually over a path of many years know as inveterate liver failure ; however , it can also happen over a course of very short time ( within 24 to 48 hour ) bang as acute liver failure .
The crusade of chronic liver failure includes hepatitis B , hepatitis C , chronic inebriation , cirrhosis of the liver , malnutrition and/or hemochromatosis .
The causes of acute liver failure include paracetamol overdose , hepatitis A , B-complex vitamin or C ( mostly in children ) , allergy reaction to certain prescribed or herbal drug and/or intake of venomous wild mushroom .
The symptom of liver-colored bankruptcy includenausea , vomiting , appetite release , diarrhea , tiredness , tartness , easy bruising and hemorrhage , abominable oedema ( swelling)/fluid buildup of abdomen ( ascites ) and dispirited extremities , varicose veins in the lower gullet and abdomen , splenomegaly , gallstones , hepatocellular carcinoma , hepatic encephalopathy ( mental confusion and disorientation ) , somnolence and/or coma .
Diagnosis and Treatment
Liver bankruptcy is hard to name with only the symptom as these symptoms overlap other disease . The definitive diagnosis of liver nonstarter admit physical examination along with liver subprogram tests ( LFTs ) through a blood sample that determine the proper operation of the liver . LFTs include ALT ( Alanine Aminotransferase ) , AST ( Aspartate Aminotransferase ) , alkaline phosphatase , bilirubin , albumin and ammonia water , which are normally unnatural in liver unsuccessful person and will show the functional deterioration of the liver .
Other rake tests can also be done to find out the exact cause of liver failure such as hepatitis A , hepatitis B , hepatitis C , prothrombin time ( PT ) and fond thrombokinase time ( PTT ) . Liver imaging is also done , which includeultrasound , CT scan , radioactive liver and spleen scan , and liver biopsy . All the above test supporter in diagnose the exact cause of liver loser .
The final intervention of liver failure is finally liver transplant . However , the patient is hospitalized and afford supportive attention depend on the causa of liver unsuccessful person , such as sometimes paracetamol poisoning can be reversed if prompt treatment is give and also in the case of viral aetiology supportive upkeep can avail in recovery of liver . If supportive attention is unresponsive then liver transplant is the only option .
It is respectable to prevent these term wherever possible such as abstaining from intoxicant in chronic alcoholism , induce vaccinations for hepatitis , refraining from drug misuse and corrode a healthy diet , to name a few .
Is It Painful To Die Of Liver Failure?
Liver is a vital Hammond organ in earn up metabolites from the blood stream that are toxic to the body . With the exit / impairment of liver function , these metabolite do not get eliminated from the body and lead to suppression of genius activity . Due to this the noesis and painful sensation perception are reduced , thus conduce to reduced predisposition to trouble in liver-colored failure affected role . Patients also have itching due to elevated grade of bilirubin and cause yellow of the skin and eye . This is address with anti - histamines and sedatives . The failing liver is ineffectual to metabolize these drugs too , hence the patient experiences less hurting / upheaval / itch . With liver failure , there is increase drugging and sleepiness ; with the progression of liver failure , there is an step-up in drowsiness and at last the patient fall away into coma . Thus , dying of liver bankruptcy is painless for the patient role as well as the relatives of the affected role who do not have to see them sustain from pain .
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