Liver metastases are tumors that have spread to the liver , but come from other organs in the body .
Cancer cells institute in metastatic liver cancer are not true liver cell , but are cells in the part of the body where the master Crab begins . Most of the clip , liver cancer is secondary .
In general , when looking at them under a microscope , the metastatic cancer cells look the same as the original Crab cells . In addition , the metastatic tumor cellular telephone and the original Crab cells unremarkably have sure rough-cut characteristics , such as the presence of certain proteins or specific alterations of the chromosome .
Is Liver Metastasis A Serious Condition?
The liver is the 2nd most common organ with metastasis ( spread of genus Cancer ) , after the lymph node . Liver metastases have been found in 30 to 70 % of patient role suffering from lethal cancer .
In the Western world , liver metastases are more common than primary liver cancer .
Liver metastasis are more frequent in patients between the ages of 50 and 70 compared with the elderly .
Liver metastasis only develop if a individual already has cancer . Some types of Crab , such as gastrointestinal genus Cancer , are more probable than others that spread to the liver . Tumors that can spread to the liver come from : Pancreas , breast , gallbladder and bile duct , colorectal , abdomen , esophagus , lung , skin ( melanoma ) , ovary ( ovarian Cancer the Crab ) and center .
Brain tumorsare the only ones that do not produce liver metastasis . The cancer usually spread to the liver because it make an passable environment for the increase of Cancer the Crab cell .
The openings in the rampart of the blood vessel of the liver allow cancer cells to set about the running cellphone of the liver ( hepatocytes ) .
The liver has good blood circulation and provide the cancer cellular telephone with the nutrient and oxygen want for growth .
Evolution of Liver Metastases
Liver metastases are a alien tissue paper that acquire inside the liver . These formations can increase in size or infiltrate other organs ( spread through the surrounding tissue ) . The metastasis maturate and compress the surrounding liver tissue .
In oecumenical , a layer of connective tissue shape around the metastasis and the surrounding tissue degrades . Large metastases can compress branches of the portal vena . Since liver metastasis rise very rapidly , they can become too large for the nutrients transported by the profligate flowing , which make the end of the cardinal part of the tissue paper .
Prognosis of Liver Metastasis
The prognosis for patients with liver metastases from the onset of symptoms is about 18 months for a solitary metastasis and only 3 month if the liver is severely affected . There have been cases of patients with histologically proven liver metastases who go more than 5 years ( the prognosis of a cancer can be 10 - 15 years ) .
The average survival for masses suffering from non - small cellphone lung cancer in the fourth stagecoach ( metastatic ) is about 8 months , although some suit of long - term natural selection have been report in affected role with lung cancer and liver metastases .
The median survival of the fittest sentence for the great unwashed with small cubicle lung cancer metastasis is 2 - 4 month without treatment and 6 - 12 month with intervention .
There is a possibleness that liveliness expectancy improves with a liver transplant and survival increases to 5 year in 75 % of patients . However , liver genus Cancer should be diagnosed at an early stage .
Liver transplantation is also an option when a person welcome an former diagnosis of Crab and liver metastasis .
If the cancer is secondary , sooner or by and by the Crab mobile phone round the new transplanted liver .
Survival rate are low-toned , even with a transplant . operative resection may improve the chance of survival , although this option is only indicated when the neoplasm only involve the tumor focus or the liver area .
Conclusion
Liver metastasis is a very serious condition . In cases where intervention is possible , aliveness expectancy increases considerably . There is a 75 % chance that the person will survive another class , 50 % will resist another 3 year and 30 % will survive at least 5 years .
In summation , with treatment such aschemotherapyand liver transplantation , an increase in the natural selection rate can be achieve .
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