Can NSAIDs Cause Peptic Ulcer Disease?
It is well do it that Nonsteroidal Antiinflammatory drug also cognise as nonsteroidal anti-inflammatory drug are frequently order for in effect control of painfulness and ignition , but also known is the fact that these nonsteroidal anti-inflammatory when used frequently and in an uncontrolled mode can cause a medical precondition called as Peptic Ulcer Disease . To encounter out how NSAIDs cause this condition , it is important to understand the functioning of NSAIDs . ordinarily the body produces two enzymes telephone COX-1 and COX-2 . These enzymes are responsible for for pain , inflammation , and fever . NSAIDs work by decoct or blocking the production of these enzymes . Another function of the COX-1 and COX-2 enzyme is that it protect the lining of the stomach from stomach acids . When there is reduce output of these enzymes due to NSAID purpose , then the stomach lining becomes vulnerable to tummy Elvis thus causing growing of ulcers in the breadbasket result in Peptic Ulcer Disease .
Who Is At Risk For Developing Peptic Ulcer Disease Due To NSAIDs?
person who use NSAID frequently for pain control are at maximal risk for developing Peptic Ulcer Disease . This is more frequent in somebody with condition like arthritis who require regular consumption of NSAIDs . The vulnerability of an individual developing Peptic Ulcer Disease due to NSAID use increases with :
What Are The Symptoms Of Peptic Ulcer Disease Caused By NSAIDs?
The most plebeian symptom of Peptic Ulcer Disease use to NSAIDs is a dull burning pain in the neck in tummy . This infliction usually hap when the belly is empty . This hurting calms down after taking antacids or after meals . This pain may last for minutes to may be even hours . This pain may die hard for months unending . Some of the other symptoms of Peptic Ulcer Disease are :
How Is Peptic Ulcer Disease Diagnosed?
for diagnose Peptic Ulcer Disease , the treating Dr. will take a history and do a detailed physical test and inquire about the symptom experienced by the individual . If Peptic Ulcer Disease is suspected , the physician will order certain lab psychometric test . The doctor may also perform an upper endoscopy to look for comportment of ulceration . A CT scan of the stomach may also be performed to look at the internal structures of the stomach to identify presence of ulcer .
What Are Treatments For Peptic Ulcer Disease Caused By NSAIDs?
There are two approach for treating Peptic Ulcer Disease make by NSAID which depends on the bearing or absence of bacterium H. Pylori .
intervention for Peptic Ulcer Disease Due To NSAIDs Without H. Pylori : If H. Pylori is abstracted in the person and it is confirm that taking nonsteroidal anti-inflammatory has make Peptic Ulcer Disease then the physician will prescribe medication that will contract production of stomach acids . Some of the medications used to reduce production of abdomen acids are :
Proton Pump inhibitor : These medications curtail dose output by obstructing the chemical mechanism which passes acid into the stomach . Some of the common medications under this category are :
Histamine Receptor Blockers : This category of medications work on by stymie histamine which facilitate Zen production . Some of the medicine in this category are :
Treatment For NSAIDs-Induced Peptic Ulcer Disease With H. Pylori Present:
In case H. Pylori is present then the treating physician will prescribe PPIs and histamine receptor blocker but dictate along with it antibiotics and other medications to drink down the bacteria .
What Happens If NSAIDs Are Still Required?
The question now come up that despite bonk the hazard of taking NSAIDs if a person still requires these medications to keep in line pain and inflammation then what happens . The answer is to confabulate the physician before starting any NSAIDs to discuss the risks versus benefit of taking these medications . There may be cases when an mortal may have developed an ulceration due to NSAIDs and then stop it but then may want to restart it again after get handling then the physician is the best person to advise whether to resume taking nonsteroidal anti-inflammatory or not .
It is also imperative that people inform their handle physician about all the medications that they take . It is then bequeath to the discretion of the cover physician whether nonsteroidal anti-inflammatory drug can be safely used in that individual or not . In both typesetter’s case , the physician will definitely prescribe PPIs or histamine sensory receptor blockers for stomach protection .
Measures To Reduce Risk Of Peptic Ulcer Disease Despite Taking NSAIDs:
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