What Is Propionic Acidemia?
Propionic Acidemia also called as PROP is an autosomal recessive trait in which the body is not able-bodied to break down certain fat and protein . This is also considered as an organic back breaker disorder , as this condition causes unnatural battery-acid work up up in the blood or piddle causing variety of complications . If Propionic Acidemia is left untreated , it can cause grave brain shortcoming and sometimes even death , although if it is identified early and prompt treatment is initiate then a lot of the complications can be avoided .
What Are The Causes Of Propionic Acidemia?
As say Propionic Acidemia is an autosomal recessionary trait which means that the faulty gene needs to be guide from both the parents . This disease is do when the enzyme propionyl - CoA carboxylase does not function appropriately . The routine of this enzyme is to break down the amino group dot , isoleucine , valine , methionine , and threonine . In cases of Propionic Acidemia , these amino loony toons are not able to be break and hence there is a build up of toxins in the blood causing wellness progeny .
What Are The Symptoms of Propionic Acidemia?
Symptoms of Propionic Acidemia Include:
How Is Propionic Acidemia Diagnosed?
The frontline method acting of diagnosing Propionic Acidemia is genetic testing , which can cut across down the faulty gene which causes Propionic Acidemia . Apart from this , tests on blood , urine or tegument are also done to confirm Propionic Acidemia .
What Are The Treatments For Propionic Acidemia?
If Propionic Acidemia is suspected or diagnose , the follow treatment measure are recommended :
Diet For Propionic Acidemia:
The tike should be given dieting which is low on protein . This can be formulate by a nutritionist who will formulate a detailed food chart which will containhigh carbohydratesas it helps keep metabolic crisis . The shaver needs to invalidate the follow foods :
Children with Propionic Acidemia need to take frequent repast and void staying hungry for long periods of clock time . This can be explained by the dietician as to how often to feed the child . Usually , the child necessitate to be feed every six hours .
Medications For Propionic Acidemia:
cubic decimetre - carnitine has exhibit to be beneficial in Propionic Acidemia as it facilitates removal of toxin from the blood and help oneself in providing vitality to the body . Certain oral antibiotics are also helpful in reducing propionic Lucy in the sky with diamonds make up in the intestine . asunder from medication supplement like Biotin is also very helpful for children with Propionic Acidemia .
Children with metabolic crises need to be treated immediately in an inpatient scene in which ordinarily bicarbonates and glucose is give intravenously . A consult with the physician is imperative before set about anymedicationor supplement for a tiddler affected with Propionic Acidemia .
Apart from all the add-on and medications , a tyke with Propionic Acidemia require to be monitored closely for ketone in the pee through urinalysis as presence of ketones in the urine is the start stage of metabolic crisis . Blood tests are also postulate sporadically to measure the levels of amino acid .
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