Antifreeze is an broker added to a urine base liquid to repress the oestrus in automobile engines . It is also call as a coolant and is normally used for cars and other vehicles . Antifreeze poisoning in human is make by the white plague of antifreeze by humans either accidently or intentionally . Antifreeze primarily contains ethylene dihydric alcohol and sometimes even methanol and isopropyl alcohol . Some of the poisonous constituent of antifreeze are ethene glycol and propene glycol .
Antifreeze poisoning can take to harmful effects and the main purpose is the ingestion of the compound present in it . Ethylene diol is fairly toxic and savour sweet being a colorless and odorless liquid . Propylene glycol just like ethylene glycol is also sweet in taste and odorless . It is mainly used to produce polymers and in the processing of food for thought . Propylene dihydric alcohol is miscible with a lot of answer and is reasonably toxic as well .
Symptoms of Antifreeze Poisoning In Humans. How is it Caused?
Some coarse symptoms of antifreeze toxic condition in humans admit
Treatment of Antifreeze Poisoning
discourse of antifreeze poisoning is possible , if symptoms are espy and timely action is taken . It is first essential to stabilize the patient to start with the treatment of antifreeze poisoning . Commonly used counterpoison for antifreeze poisoning are fomepizole or grain alcohol , if fomepizole is not available . Fomepizole is very effective if antifreeze poisoning is discover at the earliest and pay in clip . If the treatment is delay it commonly takes more time to cure . Recovery depends on the damage get and the severity of the symptoms of antifreeze poisoning .
What is Fomepizole and How Does It Help Treat Antifreeze Poisoning in Humans?
Fomepizole is one of the most of import basic medicinal drug involve for basic health structure as state by World Health Organisation .
Fomepizole is also known as 4 - methylpyrazole that is an antidote for methyl alcohol or ethene glycol poisoning . Fomepizole helps to breakdown the toxins to their active toxic metabolites . It is a very militant inhibitor of alcohol dehydrogenase enzyme that is found in the liver .
The enzyme alcohol dehydrogenase play a lively role in the metamorphosis of methanol and ethylene ethylene glycol . Fomepizole metabolizes ethylene glycol and methyl alcohol into glycoaldehyde and formaldehyde severally .
