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Turmeric- An All Rounder: 10 Beneficial Effects of Turmeric

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Turmericis biologically known as “ Curcuma longa ” is one of the extensively used spice in India , China , Pakistan and many other Asiatic land . Along with being an integral part of numerous cuisines it also serves countless health benefits . After the inquiry of many years , actual fact unwrap and came into the light that Curcuma domestica contains a yellow bioactive compound call as “ Curcumin ” which is creditworthy for the spacious spectrum of health benefits . Due to curcumin , turmeric number as an all libertine and also eff as “ Golden Goodness ” because it not only heal you externally but it is a boon for your national body also .

Turmeric- An All Rounder: 10 Beneficial Effects of Turmeric

Turmerichas been used as a medicative herbaceous plant for centuries . Here is the following pharmacological action or 10 good effects of Curcuma domestica :

Beneficial Effects of Turmeric on Stomach

H.pylori ( Helicobacter pylori ) is the destructive bacterium which is able-bodied to enrol the torso and lives in an acidulous surroundings of the human stomach . This bacteria is responsible for the increase in gastric acid and pepsin secernment which causes gastritis , stomach / peptic orduodenal ulcer . Turmeric has a bactericidal legal action against these bacterias with a faster onset of action at law and it inhibits the adhesion of H.pylori to the tum facing and flush them out from the body . Turmeric has a beneficial effect on tum as it helps assuage the ulcer by increasing the mucin secretion in the body and it also scavenges the responsive oxygen metal money [ 2 ] .

Beneficial Effect of Turmeric on Liver

Curcumin of Curcuma longa possesses protective actions on the liver by improving the detoxification ability of the liver and increase the gall secretion . It is also good in reducing hepatitis and oxidative tenseness which causes due to the highly responsive and unstable free radicals that can destruct the cells and tissues [ 3 ] . Turmeric also increases the secernment of liver enzyme glutathione S - transferase which roleplay as a chief antioxidant .

Beneficial Effect of Turmeric on Cardiovascular System

Turmeric has the ability to subjugate the austereness of numerous pathological change and heart problems such asmyocardial infarction(MI ) andatherosclerosis . It increases the Ca2 + transfer by correcting Ca2 + homoeostasis in the cardiac muscle . Turmeric also has hypercholesteremic effect as it can slenderize the blood serum cholesterol level in the hypercholesteremic country [ 4 ] .

Effect on Nervous System

Curcumin of Curcuma longa also possesses the neuroprotective action as it is able to click the blood - brain - barrier ( BBB ) due to polar structure and lower molecular weight .

Anti-inflammatory Activity

Turmeric is known as best naturally come about remedy for treating inflammation from ancient times and also view as the dependable blood purifier in Ayurveda . It removes the alien invaders and facilitate in repairing the harm .

Beneficial Antioxidant Effects of Turmeric

Oxidative damage and gratis root word are the chief culprits behind ageing and other chronic disease as they react with the many constitutive substances such as protein , fat acids and DNA . So antioxidants are very crucial for our healthy body and it is believed that turmeric contains more than 300 antioxidant and curcumin is one of the potent antioxidant , which scavenge and neutralises the oxygen spare radicals and prevent oxidization of haemoglobin . Curcumin possesses activity by maintaining the body ’s antioxidant enzymes that are superoxide dismutase , glutathione peroxidase and much more . The antioxidant activity of curcumin is due to its unique conjugated structure that has a radical - trapping ability [ 1 ] .

Beneficial Anticancer Effect of Turmeric

genus Cancer is a life - threatening disease which is caused due to uncontrolled growth of the cubicle . Curcumin in turmeric is a stiff anticancerous compound that can reduce the increment of cancerous cells , development of fresh line vessels in neoplasm that is know as angiogenesis , spreading of tumour cells that are metastasis and also responsible for for increasing the death of cancerous cells called as programmed cell death [ 1 ] . By block the activation of NF - kB , curcumin also inhibits the nitric oxide and its differential coefficient and COX-2 production which plays a major role in the onward motion of cancer .

Effects of Turmeric in Diabetes

Diabetesis a disease in which rakehell sugar level get so high and the body is unable to regulate it . Insulin is the major hormone which is produced by the pancreas and help in controlling the bloodline scratch level . So if the body is unable to produce enough insulin or if it becomes insulin impedance then the condition arise is bed asdiabetes .

Curcumin act as an anti - hyperglycemic agent which lower the blood sugar degree in following way [ 7 ] :

Effect on Depression

Curcumin in Curcuma domestica has various sophisticated action at law and anti - depressant natural process is one of them . It has been proved that Curcuma longa has promising action on major depressive disorders ( MDD).Depressionand legion medicinal drug abridge the BNDF story ( psyche derived neurotropic factor ) and recoil the brain ’s hippocampus region which is creditworthy for the learning and memory [ 8 ] . They also spay the power of the brain to regulate the hormones such as thyroid , sex and adrenal endocrine which further strike the product of neurotransmitters that are dopamine , 5-hydroxytryptamine and much more . Also , it affects the power of re-formation of mastermind cellular telephone . Curcumin has the power to deepen or promote these BNDF spirit level and neurotransmitters to rescind these unwanted changes and give rise anti - depressant bodily function .

Antimicrobial Activity

The main characteristic of anti - microbic agents is that they should be non - toxic to the body and Curcuma longa is the good antimicrobial federal agent as it does n’t have any toxic consequence on the soundbox and can be take safely 8 gigabyte day−1 [ 10 ] .

Anti - bacterial – Turmeric and it ’s phytochemical curcumin is a well - sleep together source for the antibacterial activity . It possesses bactericidal activity specifically against four bacterial genera that are :

Curcumin has anti - infecting and anti - bacterial action by acting on the biofilm instauration , virulence and quorum perception of bacteria [ 9 ] .

Anti - fungal – Curcumin is active again many fungal infection because of Aspergillus flavus and parasite such as Penicillium digitatum .

Anti - viral – Turmeric also possess the anti - vial activity and known as a refreshing drug against the HIV viral contagion as it is able to stamp down the HIV-1 integrase which is an crucial factor for the viral replication . It also reduce the HIV factor look induce by the ultraviolet light .

Also study :

reference book :

Chattopadhyay , I. , Biswas , K. , Bandyopadhyay , U. and Banerjee , R.K. , 2004 . Turmeric and curcumin : Biological activity and medicinal practical program . CURRENT SCIENCE - BANGALORE- , 87 , pp.44 - 53 .

Lee , C. J. , Lee , J. H. , Seok , J. H. , Hur , G. M. , Park , Y. C. , Seol , I. C. and Kim , Y. H. , Effects of baicalein , berberine , curcumin and hesperidin on mucin release from airline chalice cells . Planta Med . , 2003 , 69 , 523–526 .

Song , E. K. et al . , Diarylheptanoids with barren radical scavenging and hepato protective activeness in vitro from Curcuma longa . Planta Med . , 2001 , 67 , 876–877 .

Patil , T. N. and Srinivasan , M. , Hypocholesteremic effect of curcumin in rush hypercholesteremic betrayer . Indian J. Exp . Biol . , 1971 , 9 , 167–169

Kim SJ , Son TG , Park HR , Park M , Kim MS , Kim HS , et al . Curcumin rush proliferation of embryonic neuronic progenitor cellphone and neurogenesis in the grownup hippocampus . J Biol Chem . 2008;283:14497–505 . [ PMC barren clause ] [ PubMed ] .

Singh , S. and Aggarwal , B. B. , Activation of transcription factor NF - kappa B is repress by curcumin ( diferuloylmethane ) . J. Biol . Chem . , 1995 , 270 , 24995–25000 .

Sajithlal , G. B. , Chittra , P. and Chandrakasan , G. , Effect of curcumin on the ripe glycation and interbreeding - linking of collagen in diabetic rats . Biochem . Pharmacol . , 1998 , 56 , 1607–1614 .

Kulkarni , S.K. , Dhir , A. and Akula , K.K. , 2009 . potentiality of curcumin as an antidepressant drug . The Scientific World Journal , 9 , pp.1233 - 1241 .

Rudrappa T , Bais HP . Curcumin , a jazz phenolic from Curcuma longa , attenuates the virulence of Pseudomonas aeruginosa PAO1 in whole plant and animate being pathogenicity models . J Agric Food Chem . 2008;56(6 ): 1955–1962 . doi : 10.1021 / jf072591j [ PubMed ]

Tyagi , P. , Singh , M. , Kumari , H. , Kumari , A. and Mukhopadhyay , K. , 2015 . Bactericidal activity of curcumin I is tie in with damaging of bacterial membrane . PloS one , 10(3 ) , p.e0121313 .