What is Edwards Syndrome?
Edwards Syndrome , which is commonly cognise by the name of Trisomy 18 , is a rarefied genetic upset in which the moved child tends to have superfluous 18th chromosome . Edwards Syndrome is so severe that in majority of the conditions the tiddler succumbs to this circumstance before birth .
Some children who do live tend to have a myriad of complications after nascency and their quality of life is extremely poor as a result of Edwards Syndrome and they are not able to survive for more than a year or two .
Edwards Syndrome is really a clump of various congenital abnormalities with the heart , the mental capacity , kidney and the stomach which turn out as a result of this additional chromosome 18 leave in Edwards Syndrome .
Edwards Syndrome tend to affect females more than males . It has been mention in various studies that a female above the years of 30 get meaning is more than likely to give birth to a minor with Edwards Syndrome .
What are the Causes of Edwards Syndrome?
In every human being , there are 46 chromosome which occur in pair meaning that 23 pair of chromosomes in every mortal . These chromosomes are inherited from the parents .
Anatomically utter , the ovum cells in the female have 23 brace of chromosomes and the sperm cells in males have 23 duet of chromosomes . The yoke of chromosomes in females is referred to as XX and in males is referred to as XY . These chromosome are numbered from 1 - 22 . The redundant duet of chromosome that arises from chromosome 18 is found to be the main reason behind ontogenesis of Trisomy 18 or Edwards Syndrome .
child affected with Edwards Syndrome have 3 copies of chromosome 18 instead of the normal 2 which is what is responsible for the wicked symptoms that occur as a solvent of Edwards Syndrome .
What are the Symptoms of Edwards Syndrome?
In majority of the guinea pig as stated above , the small fry with Edwards Syndrome succumbs to the disease condition before parturition itself . In some case where a child with Edwards Syndrome is deliver such children are abnormally feeble and slight . They are abnormally underweight and have an extremely small head .
There may also be malformation of the ears and they may be low set . There is also underdevelopment of the back talk and the jaw . Cleft palate is also something that is commonly seen in kid with Edwards Syndrome . tiddler with Edwards Syndrome also lean to have clubbed feet and net toes .
There are also irregularity in the other parts of the body like the lung where the blood vessel may be underdeveloped or malformed . Children with Edwards Syndrome may also have congenital heart defects like atrial septal defect or ventricular septal defect which are quite living threatening conditions .
moved children may also have abnormalities in the kidney and urinary arrangement . Males may have undescended testicles as a result of Edwards Syndrome .
How is Edwards Syndrome Diagnosed?
A diagnosing of Edwards Syndrome may be done by looking at the physical features present at the sentence of the parturition of the child . Additionally , radiological studies may show the characteristic musculoskeletal abnormality seen with Edwards Syndrome .
Once Edwards Syndrome is suspected then an extensive examination of the child ’s chromosomes can be done which will distinctly show the trisomy 18 abnormality confirming the diagnosing of Edwards Syndrome . to boot , a prenatal ultrasound or an amnio before the legal transfer of the child may also help confirm a diagnosis of Edwards Syndrome .
How is Edwards Syndrome Treated?
As of now , there is no cure for Edwards Syndrome . The treatment is basically symptomatic and supportive . The discourse for such children is extremely complex .
As the prognosis of such children is passing poor and may extend for a maximum of one year ; operating room , although an option , is not carried out as the risks far outbalance the benefits of a operative operation .
Studies suggest that only 10 % of children survive beyond one year with Edwards Syndrome . The overall development of the tyke is strike due to nervous system freakishness and the child may not be able to nail the have a bun in the oven milestones as a resultant of this .
Due to abnormality in the digestive system of rules such child are feed with particular formula foods and laxative as they run to have chronic impairment due to Edwards Syndrome .
Some abnormalities for which treatments can be given are gaining control , club base , webbed toes , pneumonia , infection , high blood pressure , hydrocephalus , and sure heart defects that can be seen in tyke with Edwards Syndrome .
What is the Prognosis & Life Expectancy of Child with Edwards Syndrome?
As stated , the prognosis for Edwards Syndrome is passing poor and the maximum life expectancy is not more than a year at the most , although in majority of the cases the child succumbs to the disease condition within a matter of a couple of calendar month .
Some of the children who do live on beyond one year end up have severe physical and mental handicap that their quality of lifetime is badly compromise and they lean to be heavily dependent on others for their casual needs as a outcome of Edwards Syndrome .
