What is Somatostatinoma?
Somatostatinoma is an exceedingly rare aesculapian precondition in which there is ontogeny of malignant tumors in and around pancreas which release the hormone somatostatin . Somatostatinoma almost all the meter commence in thepancreas , although pancreas is not the only organ where these tumors develop . Somatostatinoma although being a malignant tumor is still curable if diagnose early and removed in its entirety before it has a luck to go around to other areas of the body .
As state , Somatostatinoma is a very rarified stipulation and is calculate to occur in one out of a million citizenry in the United States . Somatostatinoma are unremarkably name in individual who are in the age range of above 60 year . This is partly because of the slow growing nature of the tumor . Both Male and females can every bit be bear upon by Somatostatinoma . There are sure aesculapian conditions like Multiple Endocrine Neoplasia type 1 or MEN-1 syndrome andneurofibromatosiswhich lead off much to begin with in life and may predispose an soul to Somatostatinoma .
What Causes Somatostatinoma?
Somatostatinoma is basically caused due to uncontrolled growth of cells that create the endocrine somatostatin . These cells are institute mainly in the pancreas and the duodenum . The reason as to why the growth of these cells becomes abnormal is not yet clearly known but certain aesculapian condition like MEN-1 syndrome and neurofibromatosis contribute in development of Somatostatinoma . Pheochromocytomais yet another medical circumstance which can be held responsible for for ontogeny of Somatostatinoma .
What are the Symptoms of Somatostatinoma?
Some of the symptom of Somatostatinoma are
How is Somatostatinoma Diagnosed?
As Somatostatinoma is a very tedious grow tumour hence most of the times the diagnosis of this condition is significantly delayed and by the clock time Somatostatinoma is diagnosed it is already spread to other parts of the body . However , there are sealed symptomatic factors through which one may be able to name Somatostatinoma too soon . If an individual has predisposing factors for Somatostatinoma like MEN-2 syndrome or neurofibromatosis then Somatostatinoma can be suspected if the mortal has symptoms like those refer above .
In case a Somatostatinoma is suspected to be the cause of the symptom then it can be corroborate with a stemma attracter which will show abnormally high levels of somatostatin hormone due to the comportment of a tumor . Once the research lab studies confirm presence of mellow levels of somatostatin then further probe will be carried out in the form of radiological studies like CT and MRI scan to key the exact location of the tumor as to whether they are in the pancreas or in the duodenum .
These tests will also facilitate the Dr. curb whether the neoplasm is still localized or has it spread to let in other parts of the eubstance . This is call staging of the tumor . Once these tests are done and the solvent change state out to be positivistic then a diagnosing of Somatostatinoma is confirmed .
How is Somatostatinoma Treated?
The best style to treat Somatostatinoma is to scratch the neoplasm in its entirety and then following it up withchemotherapy . Chemotherapy is reserve for patient role in which the Somatostatinoma has spread to other persona of the body . If the tumour is identified early or has not pass around then surgical excision of the tumor is in majority of the cases remedial and the patient is completely free of Somatostatinoma .
In cases where the tumor is locate at a berth where it can not be resected then onlychemotherapyis done to belt down the cancer cell and prevent any further progression of the tumor . It should be mentioned here that chemotherapy as a treatment is not curative and is done only when the tumour is unprocurable for surgical remotion of Somatostatinoma .
