Liver is the secondly enceinte electric organ situated in the right upper quadrant of the abdomen . It is a life-sustaining organ that helps support nearly every other reed organ and has over 500 functions in the torso ; the major functions let in digestion by the product of gall ( help in rich digestion ) , metabolism , detoxification , onetime RBCs destruction , protein synthesis , regularization of hormone , to name a few . The failure of liver to carry out its function due to wipeout / terms of its cells affects near all the organ .
The Damage Of Liver Can Be Grouped Into 4 Stages , Which Are :
Stage 1: Initial Stage of Liver Disease
The first stage of liver disease include inflammation of the liver or bile duct . The firing causes abdominal pain as the body tries to fight the irritation / infection . If left untreated , the inflammation advance and causes scathe to the liver . The inflammation is two-sided and can be cover to prevent progression into 2nd phase of liver disease .
Stage 2: Fibrosis of Liver
The 2d degree of liver disease includes liver fibrosis , which cause scarring of the liver due to blockage of normal rakehell flow to the liver . The decrease in blood flow in and out of the liver leads to decreased functional capacity of the liver and make damage to the liver . The symptom might or might not be present until this stage , this stage is also treatable , and the liver damage might be reversed , as there is only small amount of liver legal injury . If not process then the liver terms progresses to the third microscope stage .
Stage 3: Cirrhosis of Liver
The untreated liver harm progression into chronic liver equipment casualty know as cirrhosis of liver , which causes permanent scarring of the liver , hamper the function as well as blood flow in and out of the liver . This stage of liver damage represent with myriad of symptom and if left untreated then it march on into the quaternary stagecoach of liver disease . The treatment of third level of liver disease include bar of further progression of disease and cover the underlying cause of the equipment casualty . This is one of the leading crusade of liver damage and death in the US .
Stage 4: Liver Failure
If the cirrhosis of the liver is not treated then it conduct to liver-colored failure . Liver nonstarter lead to 90 % of irreversible liver damage and loss of function . Along with the symptom of third stage , this phase might progress into mental confusion , coma and eventual last . This stage requires quick aesculapian attention .
What is Stage 3 Cirrhosis of Liver?
Liver cirrhosis of the liver is a chronic progression of fibrosis ( scarring ) of sizeable liver tissue leading to functional worsening of liver . Liver cirrhosis is because of chronic liver hurt cause by various conditions or disease .
Generally , cirrhosis in the initial stage is without any signs or symptom until and unless it has progressed into hard liver damage . The foretoken and symptoms when present admit weakness , lethargy , leisurely bruising and bleeding , pruritis , jaundice , ascites , sickness , vomiting , weighting loss , loss of appetency , swelling of legs , enlarged veins in the esophagus and upper venter , confusion , excessive sleepiness / somnolence and comatoseness .
There are various causes of liver cirrhosis , but the most coarse cause include chronic alcoholism , chronic viral disease ( hepatitis B and C , HIV ) and/or fatty liver . Other causes of liver cirrhosis of the liver include iron-storage disease , Wilson ’s disease , cystic fibrosis , biliary atresia , glycogen entrepot disease , Alagille syndrome , autoimmune hepatitis , primary bilious cirrhosis , infection ( schistosomiasis ) , basal sclerosing cholangitis and/or medications such as methotrexate .
Complications of Cirrhosis
The most common cause of liver cirrhosis is chronic drunkenness and chronic viral diseases . It can lead to well up in the stomach and legs causing edema of legs and ascites , splenomegaly and easy bleeding .
Diagnosis and Treatment
The diagnosis of cirrhosis of the liver is typically based on aesculapian history , forcible examination , complete blood tests , image such as ultrasound , elastography , abdominal CT , liver / bile channel MRI , endoscopy and the most authoritative trial is liver biopsy .
The most definitive treatment of liver cirrhosis includes liver graft . However , treat the underlying cause may prevent further progression of disease avoiding liver loser and death .
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