What Is The Best Treatment For Lichen Planus?
Regarding treatment of lichen planus skin disease , doctors should start by key and ensure the kick in factors :
The conventional treatment of lichen planus is ground on the app of corticoid as a basic medicine to insure inflammatory activity :
The most unremarkably used topical corticosteroids are(from low-down to highest anti - inflammatory mogul ):
The option of topical corticosteroid and the organisation regime will be made according to the severeness of the lichen planus lesion and their extension .
Some of these topical corticosteroid therapies may predispose the patient role to candidiasis ( it is a disease due to a fungus ) , which is why topical antifungals are usually prescribed as a preventative treatment or when the transmission has been give .
Topical corticosteroids are a tower in the lichen planus discussion , but if the patient is face an erosive oral lichen planus ( OLP ) that does not respond , some experts recommend the utilisation of topical tacrolimus or topical cyclosporine . However , the latter has produced contradictory solvent , due to its want of mucosal insight .
Systemic Corticosteroids : They are indicated principally in the following place :
The exercise of Orasone at a dose of 1 - 1.5 mg / kg of weight daily in a undivided dose in the former morning is recommended . This dose is used for 2 - 3 weeks and then with the same doses every other day or gradually decrease .
Intralesional Corticosteroids : Its consumption is limited to treating lichen planus wound that are very localized and/or resistant to other treatment .
Depot homework of triamcinolone acetonide ( 30 mg ) or betamethasone acetate ( 6 atomic number 12 ) are used , which are inject perilesionally once a week for 2 - 4 weeks for lichen planus .
In patients who have not improved their lichen planus lesion with corticosteroids , alternative treatments should be consider as hydroxychloroquine , azathioprine , mycophenolate , dapsone or retinoids . Current immunosuppressive therapies generally check erythema , ulcer , and unwritten symptom in patient with oral lichen planus with minimum undesirable effect .
In general , symptomless reticular lesions , if they are not far-flung , do not require therapy , only observation for changes .
Lichen planus in plaques should be approached with a more radical behaviour , such as supplant the Graeco-Roman drug - therapeutic treatment with conservative surgical discourse , thus forbid possible onco rebirth .
It is important to inform patients that oral lichen planus lesions can persevere for many year with periods of aggravation and remission . The periodical control condition must be carried out at least every six months .
It is advisable to assess patient with oral lichen planus every month during combat-ready discourse and to oversee the wound until the reduction of erythema and ulcer . Active treatment should continue until the erythema , ulcer , and symptom are controlled .
Conclusion
Current treatments for lichen planus endeavor to control irruption of rabble-rousing activities and quash complications , but discussion are empirical and little is know about the effect of other drug , dieting , physical recitation , relaxation techniques and new drug with anti - instigative natural process or immunomodulatory . There is no totally in force intervention for this disease . Molecular biology , genomics , and proteomics open unexampled path .
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