Vitamin B12 is a water - soluble vitamin that is all-important for the human body . The human body does not produce it , so it has to be suck from foods and supplements . Per mean solar day essential of masses vary with eld ; infant ( up to the age of 6 month ) require 0.4 mcg , baby ( from 6 to 12 calendar month ) necessitate 0.5 microgram , children ( between the age of 1 to 3 years ) require 0.9 mcg , tyke of 4 to 8 years of historic period require 1.2 microgram , children of 9 to 13 year of age require 1.8 mcg and soul above 14 years of age ask 2.4 mcg . The requirement in pregnant and breastfeeding woman increases to 2.6 microgram and 2.8 microgram per day severally . Although , the eubstance requires a very small amount of vitamin B12 for its normal and adequate functioning . Mostly individual above the age of 50 and those who consume vegetarian diet are substandard in this vitamin . The dietetical rootage of vitamin include animal or dairy farm sources such as fish , eggs , essence , poultry , milk , and cheese .
What Is The Effect of Vitamin B12 Deficiency?
The effect of vitamin B12 insufficiency can be bear on to its various functions in the organic structure . It is of the essence for biochemical reactions in cells , which are needed for the formation of DNA , various protein , hormones and avoirdupois . It also play an important role in the conversion of homocysteine to methionine . It cultivate along with folic acid that helps in various biochemical pathways and also helps transform nonoperational folic acid to its active form .
Vitamin B12 is demand for desoxyribonucleic acid production and normal cellphone section , so adequate amount is take at the time of gestation for normal maturation and growth of foetus . The want of vitamin B12 in the body hampers DNA synthesis and cell proliferation .
It is also necessary for the production of normal cherry-red blood cells in the bone marrow . Its lack in the bone gist dissuade ripening of red blood cells and decrease ruby blood cells in the lineage leading to pernicious anemia .
It is also necessary for the upkeep of normal gastrointestinal facing . The deficiency of vitamin B12 in the facing of digestive tract leads to geological formation of large abnormal cell in the stomachic lining interferes with normal engrossment nutrient and also causes symptoms of soreness in mouth and tongue .
It is also all-important for the maturation and optimum operation of the brain and nervous system . It is required in the formation of myeline sheath ( the protective covering of nerve fibre ) and also in the product of neurotransmitters ( chemical that help in the transmission of nervus signals between jail cell ) . B12 deficiency conduct to price of mettle cells in the brain andspinal cordcausing blanket damage to myeline sheath . If the deficiency persists for long , it lead to symptoms of numbness and tingle , balance problems , store loss , anddepression .
B12 is also necessary for optimum osseous tissue health , as its deficiency has been linked to osteoporosis leading to unannealed bones and increased endangerment for break .
B12 is necessary for immunity , as its want is associated with abnormalcy of the resistant system . A subject suggested that someone with low B12 level react poorly to pneumonia vaccinum . It is also associate with decrease functionality of white line cells and increased susceptibility to infection such as TB .
Symptoms of Vitamin B12 Deficiency
Vitamin B12 deficiency can affect nervous organisation , GI system of rules , cardiovascular system of rules as well as bone health . The insufficiency symptom include spiritlessness , tingle , dizziness , store loss , natural depression , balance problem , confusion , dementedness , fatigue , quivering , tachycardia , abruptness of hint , sickness , want of appetite , weight loss , diarrhea , stultification , soreness and inflammation in tongue with loss of papilla , difficulty walking , muscle weakness , peevishness , and/or vision loss .
Vitamin B12 deficiency can be stimulate by conditions such as atrophic gastritis , Crohn ’s disease , Celiac disease to name a few . Vitamin B12 deficiency can be prevent by taking a diet rich in Pisces , eggs , and dairy . The deficiency can be make up by vitamin B12 injection , oral supplements , or nasal spraying .
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