What Is The Most Common Type Of Interstitial Lung Disease?

Idiopathic Pulmonary Fibrosis is the most vernacular case of interstitial lung disease . It is a debilitating and chronic disease characterized by a progressive decrease in lung mapping that makes breathing more unmanageable . The nomenclature “ pneumonic fibrosis ” refers to the healing of lung tissue paper , which causes a progressive decrement in lung purpose and as a consequence a respiratory deficiency that decline over sentence .

Diffuse interstitial lung diseases ( DILD ) constitute around 150 similar entities in which it is known as the causal federal agent in just a third of case .

Idiopathic Interstitial Pneumonia

They constitute a group of diseases of strange etiology with specific machine characteristic .

Idiopathic Pulmonary Fibrosis

It is a character of DILD with the histologic manifestation of usual interstitialpneumonia(UIP ) . Idiopathic Pulmonary Fibrosis is the most frequent DILD . Its etiology is unknown .

It ordinarily occurs after 50 years , with an insidious attack , in the sort of progressivedyspneaanddry cough .

Non-specific Interstitial Pneumonia (NSIP)

Some years ago , it began to be observed that some biopsy of patients with diffuse interstitial lung disease did not fit any well - delineate histologic pattern of the classic interstitial pneumonia , this is called nonspecific interstitial pneumonia ( NSIP ) .

Cryptogenic Organized Pneumonia (COP)

It constitutes an active fibrosing appendage that primarily touch distal bronchioles , alveolar epithelial duct , and peribronchial alveoli , classically known as bronchiolitis obliterans mastermind pneumonia ( BOOP ) . The disease presents a subacute onset , with a reformist cough and dyspnea , often systemic symptom such as fever , asthenia and exercising weight loss . In some cases , the onset may be intense in the form of severe respiratory failure . BOOP may be due to legion causes and may be a determination in different entities , such as hypersensitivity pneumonia , nonspecific interstitial pneumonia , eosinophilic pneumonia or Langerhans cubicle histiocytosis .

For the diagnosis , it is required the connection of the clinical - radiological data previously describe with the histopathological demo of organized pneumonia in a lung biopsy sampling .

The prognosis is good . Among the grammatical case with the great risk would be the secondary to immunological disease , collagen , drug , and environmental factors . For the discourse , glucocorticoids are dish out at exchangeable State Department to those used in the NSIP .

Acute Interstitial Pneumonia (AIP)

The AIP is a rapidly reformist entity characterized by the presence of diffuse alveolar harm ( DAD ) in the lung parenchyma . The onset of symptoms is insidious , sometimes as a flu - like syndrome that can progress to hard respiratory nonstarter requiring mechanically skillful ventilation .

Respiratory Bronchiolitis-Interstitial Lung Disease (RB-ILD)

It is instantly tie in to baccy , it appears in smoker who fume more than 30 packs per year . This is a histopathological wound found in smoke patients , characterise by the bearing of macrophages loaded with a okay pigment inside the respiratory bronchioles . It is seldom symptomatic and is unremarkably associate with a dysfunction of small airways . However , in rare cases , it occurs in the form of the interstitial disease with plain pulmonary symptomatology and abnormalities of respiratory and radiological subprogram tests . That ’s when we talk about the RB - ILD .

Desquamative Interstitial Pneumonia (DIP)

The name grow in the belief that the key characteristic of this character of injuries was the “ desquamation ” of the epithelial cells . However , now it is sleep with that it is really of sum of intraalveolar macrophages . It is consider as the modern stage of the RB - ILD , due to its association with tobacco plant and the similarity of the anatomopathological findings .

Lymphocytic Interstitial Pneumonia (NIL)

It is characterise by the existence of interstitial lymphocytic infiltrates in the pulmonic parenchyma .

Many generator choose to classify NIL in the epigraph of pulmonic lymphoproliferative disorder . This is so because in many compositor’s case it has been described the evolution towards lymphomas and NIL has gone to be considered then as a preneoplastic clinical presentment .

In fact , many typeface describe as NIL were credibly non - Hodgkin ’s lymphomas of low score and phenotype B since its origin .

The distinction between NIL and a lymphoma , therefore , is difficult to do just apply routine techniques . It can portray a subacute onset with a cough , progressive dyspnea ( difficult breathing ) and systemic symptom ( arthralgias which mean pain in the joints , fever , weight loss . )